OntologyTerm cranial neural crest

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   May 11th, 2017 at 4:19pm

Details

definition 
Neural crest cells (NCCs) originating in the anterior part of the developing embryo and residing between the mid-diencephalon and the forming hindbrain; cranial NCCs migrate dorsolaterally to form the craniofacial mesenchyme that differentiates into various craniofacial cartilages and bones, cranial neurons, glia, and connective tissues of the face; these cells enter the pharyngeal pouches and arches where they give rise to thymic cells, bones of the middle ear and jaw (mandible), and the odontoblasts of the tooth primordia; like their counterparts in the trunk, cranial NCCs also contribute to the developing peripheral nervous system, along with the pigmented cell (i.e. melanocyte) lineage. (UBERON)
namespace 
http://purl.obolibrary.org/obo
parents 
  1. structure with developmental contribution from neural crest
  2. ectoderm-derived structure
  3. embryonic tissue
  4. anatomical structure
preferred_name 
cranial neural crest
references 
  1. None
slim_terms 
  1. ectoderm
source_ontologies 
  1. Uberon
  2. Experimental Factor Ontology
synonyms 
  1. cranial NCC population
  2. head NCC population
  3. cephalic neural crest
  4. CNC
term_id 
UBERON:0003099
term_name 
cranial neural crest
term_url 
http://purl.obolibrary.org/obo/UBERON_0003099