OntologyTerm
chronic childhood arthritis

released
View JSON
   May 11th, 2017 at 4:12pm

Details

definition 
Juvenile idiopathic arthritis (JIA) is the term used to describe a group of inflammatory articular disorders of unknown cause that begin before the age of 16 and last over 6 weeks. The term juvenile idiopathic arthritis was chosen to signify the absence of any known mechanism underlying the disorder and to highlight the necessity of excluding other types of arthritis occurring in well defined diseases (in particular arthritis occurring in association with infectious, inflammatory and haematooncologic diseases). -- Juvenile idiopathic arthritis (JIA), also known as juvenile rheumatoid arthritis (JRA), is the most common form of arthritis in children and adolescents. (Juvenile in this context refers to an onset before age 16, idiopathic refers to a condition with no defined cause, and arthritis is the inflammation of the synovium of a joint.) JIA is an autoimmune, non-infective, inflammatory joint disease of more than 6 weeks duration in children less than 16 years of age. The disease commonly occurs in children from the ages of 7 to 12, but it may occur in adolescents as old as 15 years of age, as well as in infants. It is a subset of arthritis seen in childhood, which may be transient and self-limited or chronic. It differs significantly from arthritis commonly seen in adults (osteoarthritis, rheumatoid arthritis), and other types of arthritis that can present in childhood which are chronic conditions (e.g. psoriatic arthritis and ankylosing spondylitis). Aetiopathology is similar to rheumatoid arthritis but with less marked cartilage erosion, and joint instability and absent rheumatoid factor. JIA affects approximately 1 in 1,000 children in any given year, with about 1 in 10,000 having a more severe form. (EFO)
namespace 
http://www.ebi.ac.uk/efo
parents 
  1. chronic disease
  2. rheumatic disease
  3. arthritis
  4. autoimmune disease
preferred_name 
chronic childhood arthritis
references 
  1. None
source_ontologies 
  1. Experimental Factor Ontology
synonyms 
  1. Arthritis (juvenile idiopathic)
  2. Juvenile rheumatoid a.
  3. breast myoepithelial carcinoma
  4. Juvenile rheumatoid arthritis, NOS
  5. Juvenile idiopathic arthritis
  6. Juvenile idiopathic arthritis (disorder)
  7. JIA
  8. chronic childhood arthritis
  9. juvenile idiopathic arthritis
  10. Juvenile Rheumatoid Arthritis
  11. arthritis, juvenile rheumatoid
  12. Juvenile rheumatoid arthritis (disorder)
  13. juvenile arthritis
  14. Juvenile chronic arthritis (disorder)
  15. Juvenile rheumatoid arthritis NOS (disorder)
  16. Juvenile seropositive polyarthritis
  17. juvenile rheumatoid arthritis
  18. acute juvenile rheumatoid arthritis
  19. pauciarticular juvenile arthritis
  20. pauciarticular onset juvenile chronic arthritis
  21. monarticular juvenile rheumatoid arthritis
  22. systemic juvenile rheumatoid arthritis
term_id 
EFO:0002609
term_name 
juvenile idiopathic arthritis
term_url 
http://www.ebi.ac.uk/efo/EFO_0002609