OntologyTerm
neoplasm of mature B-cells

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   May 11th, 2017 at 4:07pm

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definition 
A neoplasm of follicle center B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001). -- A neoplasm of follicle centre B cells which has at least a partial follicular pattern. Follicular lymphomas comprise about 35% of adult non-Hodgkin lymphomas in the U.S. and 22% worldwide. Most patients have widespread disease at diagnosis. Morphologically, follicular lymphomas are classified as Grade 1, Grade 2, and Grade 3, depending on the percentage of the large lymphocytes present. The vast majority of cases (70-95%) express the BCL-2 rearrangement [t(14;18)]. Histological grade correlates with prognosis. Grades 1 and 2 follicular lymphomas are indolent and grade 3 is more aggressive (adapted from WHO, 2001). (EFO)
namespace 
http://www.ebi.ac.uk/efo
parents 
  1. B-cell neoplasm
preferred_name 
neoplasm of mature B-cells
references 
  1. None
source_ontologies 
  1. Experimental Factor Ontology
synonyms 
  1. Follicular Mixed Cell Lymphoma
  2. Disease, Brill-Symmers
  3. LYMPHOMA LARGE FOLLIC
  4. peripheral B-cell neoplasm
  5. Follicular Lymphoma
  6. Brill-Symmers Disease
  7. Histiocytic Lymphomas, Nodular
  8. Lymphoma, Large Lymphoid, Nodular
  9. Mixed-Cell Lymphoma, Follicular
  10. Follicular Large Cell Lymphoma
  11. Non-Hodgkin's Lymphoma B-Cell
  12. B-Cell Non-Hodgkin's Lymphoma
  13. Lymphoma, Follicular Large-Cell
  14. LARGE LYMPHOMA FOLLIC
  15. Mixed-Cell Lymphomas, Follicular
  16. Lymphoma, Large-Cell, Follicular
  17. Lymphomas, Giant Follicular
  18. Nodular Histiocytic Lymphoma
  19. B-cell lymphoma
  20. Follicular Lymphoma, Grade 2
  21. SMALL FOLLIC CENTER LYMPHOMA
  22. Lymphoma, Nodular, Mixed Lymphocytic-Histiocytic
  23. Lymphoma, Nodular, Mixed Lymphocytic Histiocytic
  24. Lymphoma, Follicular, Mixed Small and Large Lymphoid
  25. Follicular Lymphomas
  26. Large-Cell Lymphoma, Follicular
  27. Lymphoma, Nodular, Mixed Small and Large Cell
  28. Lymphomas, Nodular
  29. Follicular Large-Cell Lymphoma
  30. MIXED LYMPHOMA FOLLIC
  31. Nodular Large Follicular Center-Cell Lymphoma
  32. Lymphoma, Follicular, Grade 3
  33. LYMPHOMA FOLLIC
  34. Histiocytic Lymphoma, Nodular
  35. Lymphoma, Small Cleaved-Cell, Follicular
  36. Follicular Lymphomas, Giant
  37. Lymphoma, Follicular Large Cell
  38. Follicular Large-Cell Lymphomas
  39. Nodular Lymphoma
  40. Small Follicular Center Cell Lymphoma
  41. Lymphoma, Giant Follicular
  42. Brill Symmers Disease
  43. Follicular Mixed-Cell Lymphoma
  44. Lymphomas, Follicular Mixed-Cell
  45. Follicular Lymphoma, Grade 1
  46. Nodular Lymphomas
  47. Lymphoma, Nodular Histiocytic
  48. Lymphomas Non-Hodgkin's B-Cell
  49. Giant Follicular Lymphomas
  50. LYMPHOMA SMALL LYMPHOID FOLLIC
  51. LYMPHOMA FOLLIC SMALL LARGE CLEAVED
  52. LYMPHOMA FOLLIC MIXED LYMPHOCYTIC HISTIOCYTIC
  53. Lymphoma, Small Cleaved Cell, Follicular
  54. Small Follicular Center-Cell Lymphoma
  55. Lymphocytic Lymphoma, Nodular, Poorly-Differentiated
  56. Lymphoma, Mixed-Cell, Follicular
  57. Lymphoma, Follicular, Mixed Cell
  58. Large Cell Lymphoma, Follicular
  59. LYMPHOMA NODULAR LARGE FOLLIC CENTER
  60. FOLLIC LYMPHOMA
  61. Lymphoma, Lymphocytic, Nodular, Poorly-Differentiated
  62. Lymphomas, Nodular Histiocytic
  63. Lymphoma, Follicular, Grade 2
  64. Small Cleaved-Cell Lymphoma, Follicular
  65. LYMPHOMA SMALL FOLLIC CENTER
  66. LYMPHOMA SMALL CLEAVED CELL FOLLIC
  67. LYMPHOMA SMALL CLEAVED FOLLIC
  68. Lymphoma, Follicular
  69. Lymphoma, Nodular, Large Follicular Center-Cell
  70. Small Cleaved Cell Lymphoma, Follicular
  71. LYMPHOMA FOLLIC MIXED SMALL LARGE LYMPHOID
  72. Lymphoma, Histiocytic, Nodular
  73. Follicular Lymphoma, Giant
  74. Follicular Lymphoma, Grade 3
  75. Lymphoma, Nodular
  76. LYMPHOCYTIC LYMPHOMA NODULAR POORLY DIFFER
  77. Nodular Large Follicular Center Cell Lymphoma
  78. Large Lymphoid Lymphoma, Nodular
  79. Lymphomas, Follicular Large-Cell
  80. LYMPHOMA MIXED FOLLIC
  81. Giant Follicular Lymphoma
  82. Follicular Mixed-Cell Lymphomas
  83. Nodular Histiocytic Lymphomas
  84. GIANT FOLLIC LYMPHOMA
  85. Lymphoma, Follicular, Grade 1
  86. Lymphoma, Large Cell, Follicular
  87. B-Cell Non-Hodgkin Lymphoma
  88. Lymphoma, Follicular, Small and Large Cleaved Cell
  89. Lymphomas, Follicular
  90. NODULAR LARGE FOLLIC CENTER LYMPHOMA
  91. Lymphocytic Lymphoma, Nodular, Poorly Differentiated
  92. Lymphoma, Lymphocytic, Nodular, Poorly Differentiated
  93. FOLLIC LARGE LYMPHOMA
  94. Non-Hodgkin's B-Cell Lymphoma
  95. FOLLIC MIXED LYMPHOMA
  96. Mixed Cell Lymphoma, Follicular
  97. LYMPHOMA FOLLIC MIXED
  98. BRILL SYMMERS DIS
  99. Lymphoma, Small Lymphoid, Follicular
  100. LYMPHOMA FOLLIC LARGE
  101. LYMPHOMA GIANT FOLLIC
  102. Large-Cell Lymphomas, Follicular
  103. Lymphoma, Follicular, Small and Large Cleaved-Cell
  104. FOLLIC LYMPHOMA GIANT
  105. mature B-cell lymphocytic neoplasm
  106. Lymphoma, Nodular, Large Follicular Center Cell
  107. neoplasm of mature B-cells
  108. Lymphoma, Follicular, Mixed Lymphocytic-Histiocytic
  109. B-Cell Non Hodgkin's Lymphoma
  110. Lymphoma, Follicular Mixed-Cell
  111. SMALL CLEAVED LYMPHOMA FOLLIC
  112. LYMPHOMA NODULAR MIXED SMALL LARGE
  113. Lymphoma, Small Follicular Center-Cell
  114. Lymphoma, Small Follicular Center Cell
  115. LYMPHOMA LYMPHOCYTIC NODULAR POORLY DIFFER
  116. mature B-cell neoplasm
term_id 
EFO:0000096
term_name 
neoplasm of mature B-cells
term_url 
http://www.ebi.ac.uk/efo/EFO_0000096