OntologyTerm mesenchymal cell

released
   May 11th, 2017 at 6:49pm

Details


definition 
A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. In humans, this cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. -- A connective tissue cell that normally gives rise to other cells that are organized as three-dimensional masses. This cell type is CD73-positive, CD90-positive, CD105-positive, CD45-negative, CD34-negative, and MHCII-negative. They may further differentiate into osteoblasts, adipocytes, myocytes, neurons, or chondroblasts in vitro. Originally described as residing in the bone marrow, this cell type is now known to reside in many, if not all, adult organs. (UBERON)
namespace 
http://purl.obolibrary.org/obo
preferred_name 
mesenchymal cell
references 
  1. None
slim_terms 
source_ontologies 
synonyms 
  1. bone marrow stromal cells
  2. colony-forming unit-fibroblast
  3. marrow stromal cells
  4. BMSC
term_id 
CL:0000134
term_name 
mesenchymal stem cell
term_url 
http://purl.obolibrary.org/obo/CL_0000134