ExperimentSetReplicate

ExperimentSet4DNESW7WYVHO
released
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in situ Hi-C on compound heterozygous Crispr modified TBX5 LOF with 1 bp insertion causing frameshift and 8 bp deletion in WTC-11 iPSC cells differentiated for 20 days to atrial cardiac myocytes.

   December 18th, 2024 at 5:04pm
Source Publication
Dose-dependent sensitivity of human 3D chromatin to a heart disease-linked transcription factor
Grant ZL, Kuang S, et al., bioRxiv 2025

Experiment Set Properties  

Set Type 
Replicate
Organism 
H. sapiens
Sample Type 
in vitro differentiated cells
Sample 
WTC-11 differentiated to cardiac muscle cell
Experiment Type(s) 
in situ Hi-C
Modification Type 
Crispr
Treatment Type 
None
Assay Details 
Enzyme: DdeI and DpnII

10 Processed Files

Quality Metrics

Experiment
For File
Filtered Reads
Cis reads (>20kb)
Short cis reads
Trans Reads
Report
Details
From Multiple Experiments
4DNESW7WYVHO
Multiple Experiments
File
Contact List-combined (pairs)
4DNFILP3EWF3
927.02m
36.682%
47.276%
16.042%
Experiment
4DNEXLCCHOPJ
Bio Rep 1, Tec Rep 1
in situ Hi-C on WTC-11 differentiated to cardiac muscle cell with DdeI and DpnII
File
Contact List-replicate (pairs)
4DNFIDXYNVFW
527.1m
36.397%
47.903%
15.7%
Experiment
4DNEX1JCZ446
Bio Rep 2, Tec Rep 1
in situ Hi-C on WTC-11 differentiated to cardiac muscle cell with DdeI and DpnII
File
Contact List-replicate (pairs)
4DNFIWPS6OHH
467.37m
37.486%
44.089%
18.424%
Experiment
For File
Failed Balancing
Details
From Multiple Experiments
4DNESW7WYVHO
Multiple Experiments
File
Contact Matrix (mcool)
4DNFI52OLNJ4
None