ExperimentSetReplicate

ExperimentSet4DNES8CZNQCU
released
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Replicates of in situ Hi-C on compound heterozygous Crispr modified TBX5 LOF with 1 bp deletion causing frameshift and 8 bp insertion in WTC-11 iPSC cells differentiated for 23 days to cardiac myocytes.

   August 18th, 2022 at 9:14pm
Source Publication
Dose-dependent sensitivity of human 3D chromatin to a heart disease-linked transcription factor
Grant ZL, Kuang S, et al., bioRxiv 2025

Assay Description  

Experiment Set Properties  

Set Type 
Replicate
Organism 
H. sapiens
Sample Type 
in vitro differentiated cells
Sample 
WTC-11 differentiated to cardiac muscle cell
Experiment Type(s) 
in situ Hi-C
Modification Type 
Crispr
Treatment Type 
None
Assay Details 
Enzyme: Arima - A1, A2

10 Processed Files

Quality Metrics

Experiment
For File
Filtered Reads
Cis reads (>20kb)
Short cis reads
Trans Reads
Details
From Multiple Experiments
4DNES8CZNQCU
Multiple Experiments
File
Contact List-combined (pairs)
4DNFI3ZW8EC8
1.29 billion
51.091%
26.608%
22.301%
Experiment
4DNEXWNU1ZQ7
Bio Rep 1, Tec Rep 1
in situ Hi-C on WTC-11 differentiated to cardiac muscle cell with Arima - A1, A2
File
Contact List-replicate (pairs)
4DNFI7UXHRY7
620.08m
54.538%
25.501%
19.961%
Experiment
4DNEXGIW4SCL
Bio Rep 2, Tec Rep 1
in situ Hi-C on WTC-11 differentiated to cardiac muscle cell with Arima - A1, A2
File
Contact List-replicate (pairs)
4DNFI3BG6Z9Q
670.94m
47.905%
27.631%
24.463%
Experiment
For File
Failed Balancing
Details
From Multiple Experiments
4DNES8CZNQCU
Multiple Experiments
File
Contact Matrix (mcool)
4DNFIL2ODN92
None
Experiment
For File
Total Reads
Unmapped Reads
Multimapped Reads
Duplicate Reads
Walks
Minor Contigs
Details
Experiment
4DNEXWNU1ZQ7
Bio Rep 1, Tec Rep 1
in situ Hi-C on WTC-11 differentiated to cardiac muscle cell with Arima - A1, A2
File
Alignments (bam)
4DNFIBLJYRSM
1.21 billion
5.254%
7.71%
21.508%
14.418%
0.197%
Experiment
4DNEXGIW4SCL
Bio Rep 2, Tec Rep 1
in situ Hi-C on WTC-11 differentiated to cardiac muscle cell with Arima - A1, A2
File
Alignments (bam)
4DNFI99QXVYD
1.25 billion
4.414%
7.451%
22.15%
12.155%
0.24%