Chromatin tracing (MINA) of an 840-kb region of chrX (chrX:77657854-78497854, GRCh38) in human female IMR-90 cells, with DNA methylation (cytosine-C5) inhibitor (ZdCyc). The data presented here is derived from 1 biological replicate.
TAD-like single-cell domain structures exist on both active and inactive X chromosomes and persist under epigenetic perturbations.
Cheng Y, Liu M, et al., Genome biology 2021
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