OntologyTerm
atypical teratoid rhabdoid tumor

released
View JSON
   July 13th, 2017 at 6:53pm

Details

definition 
An aggressive malignant embryonal neoplasm arising from the central nervous system. It is composed of cells with a large eccentric nucleus, prominent nucleolus, and abundant cytoplasm. Mutations of the INI1 gene or very rarely SMARCA4 (BRG1) gene are present. The vast majority of cases occur in childhood. Symptoms include lethargy, vomiting, cranial nerve palsy, headache, and hemiplegia. -- Atypical teratoid rhabdoid tumor (ATRT) is a highly malignant central nervous system (CNS) rhabdoid tumor (RT) found almost exclusively in children. (EFO)
namespace 
http://www.ebi.ac.uk/efo
parents 
  1. central nervous system sarcoma
  2. no view permissions
  3. malignant rhabdoid tumour
preferred_name 
atypical teratoid rhabdoid tumor
references 
  1. None
source_ontologies 
  1. Experimental Factor Ontology
synonyms 
  1. Atypical Teratoid/Rhabdoid Tumor
  2. AT/RT
  3. malignant rhabdoid neoplasm of the brain
  4. central nervous system rhabdoid neoplasm
  5. CNS rhabdoid neoplasm
  6. rhabdoid tumor of the CNS
  7. primary malignant rhabdoid tumor of brain
  8. atypical teratoid/rhabdoid tumor
  9. central nervous system rhabdoid tumor
  10. rhabdoid tumor of the central nervous system
  11. rhabdoid neoplasm of the central nervous system
  12. primary malignant rhabdoid tumor of the brain
  13. atypical teratoid rhabdoid tumor
  14. ATT/RHT
  15. rhabdoid neoplasm of central nervous system
  16. primary malignant rhabdoid neoplasm of brain
  17. ATRT
  18. primary malignant brain rhabdoid neoplasm
  19. malignant brain rhabdoid tumor
  20. atypical teratoid/rhabdoid tumor (morphologic abnormality)
  21. malignant rhabdoid neoplasm of brain
  22. malignant rhabdoid tumor of the brain
  23. rhabdoid tumor of central nervous system
  24. primary malignant rhabdoid neoplasm of the brain
  25. CNS rhabdoid tumor
  26. atypical teratoid/rhabdoid tumor (WHO grade IV)
  27. malignant rhabdoid tumor of brain
  28. malignant brain rhabdoid neoplasm
  29. primary malignant brain rhabdoid tumor
  30. rhabdoid neoplasm of CNS
  31. rhabdoid neoplasm of the CNS
  32. rhabdoid tumor of CNS
term_id 
EFO:1002008
term_name 
atypical teratoid rhabdoid tumor
term_url 
http://www.ebi.ac.uk/efo/EFO_1002008